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Detection of structural variations involved in hereditary diseases
The Molecular Combing Technology, through an accurate single DNA molecule analysis approach, responds to recurrent challenges in molecular diagnostics, including the detection of large genomic rearrangements and complex structural variations. Genomic Vision provides objective and comprehensive means to genetic diagnostic and offers a new perspective in molecular analysis.
From physical mapping of DNA over large regions of interests, to dynamic studies of DNA replication
Genomic Vision’s proprietary single DNA analysis technology combines Molecular Combing; isolation and
linearization genomic DNA, with a unique targeting and detection strategy, the Genomic Morse Code. Genomic
Vision offers a versatile approach to probe the genome and gain insight into the structure and function of
Discover our new automated high-resolution imaging system
FiberVisionS and FiberStudio enable high-resolution imaging of single DNA molecules and provide a powerful to analyze hundreds of DNA molecules.
Genomic Vision’s diagnostic assay provides an accurate number of D4Z4 repeats and the haplotype for each chromosome 4 and 10, and a full panorama of the 4q35 and 10q26 loci (p13E15del, molecular recombination within D4Z4).
Replication Combing Assay
The Replication Combing Assay (RCA) provides a unique, high resolution, single molecule approach to monitor both spatial and temporal characteristics of DNA replication in a single experiment.
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Molecular Combing Platform
We pioneered the development of the Molecular Combing Platform based on our direct DNA analysis technology: a set of state-of-the-art tools that facilitates a standardized workflow from DNA extraction to data analysis, while resolving important limitations of other DNA fiber assays.
A proprietary technique to untangle single DNA molecules for direct visualization and analysis
Molecular Combing is a user-friendly procedure for the stretching and assembly of millions of large DNA fragments. The DNA is attached and “combed” on a specially-treated glass surface using an automated process.
Genomic Morse Code
A unique language for a clear understanding of DNA modifications
We have developed a unique proprietary detection strategy called the Genomic Morse Code (GMC) for comprehensive analysis and physical mapping of target regions on stretched DNA.